Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LAP3 | P28838 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | ALPG | P10696 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616198 | 1.00 | TSHR (0.41) | TSHRLAP3CA12CA1CA2 | |
| Isobutane SCHEMBL27082315 | 0.97 | TSHR (0.39) | TSHRLAP3CA12CA1CA2 | |
| SCHEMBL9182978 | 0.97 | TSHR (0.39) | TSHRLAP3CA12CA1CA2 | |
| Ammonia Solution, Strong SCHEMBL10937835 | 0.97 | TSHR (0.39) | TSHRLAP3CA12CA1CA2 | |
| SCHEMBL1914111 | 0.97 | TSHR (0.39) | TSHRLAP3CA12CA1CA2 | |
| SCHEMBL2035248 | 0.97 | TSHR (0.39) | TSHRLAP3CA12CA1CA2 | |
| Isobutane SCHEMBL1395620 | 0.94 | TSHR (0.37) | TSHRLAP3CA12CA1CA2 | |
| Butane SCHEMBL17765810 | 0.91 | TSHR (0.35) | TSHRLAP3MMP1MMP2MMP3 | |
| SCHEMBL8812783 | 0.83 | TSHR (0.39) | TSHRLAP3MMP1MMP2MMP3 | |
| Isobutane SCHEMBL11753394 | 0.81 | TSHR (0.35) | TSHRLAP3ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748862-B1 | Lubricating compositions, functional fluids and greases containing thiophosphorus esters or their salts with an oxyalkylene group, and methods of using the same | LUBRIZOL CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| US-5968880-A | OIL CONTAINING METAL-FREE ANTIWEAR AGENT/RUST INHIBITOR; EXTREME PRESSURE LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| US-5622923-A | HAVING IMPROVED ANTIWEAR, EXTREME PRESSURE, ANTIOXIDANT, RUST INHIBITOR PROPERTIES | THE LUBRIZOL CORPORATION (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0748862-A2 | Lubricating compositions, functional fluids and greases containing thiophosphorus esters or their salts with an oxyalkylene group, and methods of using the same | The Lubrizol Corporation (an Ohio corporation) (US) | 1996-12-18 | — | — | EP | disclosed |