Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538286 | 0.89 | TSHR (0.50) | MEN1KMT2APGRPOLBALDH1A1 | |
| Laquinimod SCHEMBL29438575 | 0.87 | TP53 (0.50) | MEN1KMT2APGREGFRALDH1A1 | |
| Laquinimod SCHEMBL39440 | 0.87 | TP53 (0.50) | MEN1KMT2APGREGFRALDH1A1 | |
| Laquinimod SCHEMBL1573702 | 0.86 | TP53 (0.49) | MEN1KMT2APGREGFRALDH1A1 | |
| Laquinimod SCHEMBL1573491 | 0.86 | TP53 (0.49) | MEN1KMT2APGREGFRALDH1A1 | |
| Laquinimod SCHEMBL1573337 | 0.86 | TP53 (0.49) | MEN1KMT2APGREGFRALDH1A1 | |
| Laquinimod SCHEMBL1573704 | 0.86 | TP53 (0.49) | MEN1KMT2APGREGFRALDH1A1 | |
| SCHEMBL8136645 | 0.86 | MEN1 (0.44) | MEN1KMT2APGRPOLBALDH1A1 | |
| SCHEMBL7615154 | 0.86 | MEN1 (0.44) | MEN1KMT2APGRPOLBALDH1A1 | |
| SCHEMBL7597091 | 0.86 | HDAC4 (0.55) | MEN1KMT2APGRPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073639-B1 | QUINOLINE DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6077851-A | USED FOR TREATMENT OF DISEASES RESULTING FROM AUTOIMMUNITY SUCH AS MULTIPLE SCLEROSIS, INSULIN-DEPENDENT DIABETES MELLITUS, SYSTEMIC LUPUS ERYTHEMATOSUS, RHEUMATOID ARTHRITIS, INFAMMATORY BOWEL DISEASE AND PSORIASIS; LAQUINIMOD AS NEW CHEMICAL ENTITY | ACTIVE BIOTECH AB (SE) | 2000-06-20 | — | — | US | disclosed |