SCHEMBL7598014

SCHEMBL7598014

BrCCCCCCCCCCCCCCCCCCCCCCBr

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ACHE P22303 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL688421 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL129069 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL67512 1.00
SCHEMBL10962222 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL53228 1.00
SCHEMBL31090 1.00
SCHEMBL8431581 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL8147317 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL687165 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE
SCHEMBL2535724 1.00 TSHR (0.46) TSHRHSD17B10TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0917465-B1 ANTIMALARIAL AND ANTI-BABESIOSIS AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AGENTS VIRBAC SA (FR) 2002-11-20 EP disclosed
US-6096788-A MOLECULES CONTAINING TWO QUATERNARY AMMONIUM GROUPS ON ENDS OF HYDROCARBON CHAIN VIRBAC S.A. (FR) 2000-08-01 US disclosed
US-6090508-A RECORDING AND ERASING METHOD UTILIZING REVERSIBLE CHANGES IN CRYSTALLINE STATE OF RECORDING LAYER COMPRISING OPTICAL ANISOTROPIC THIN-FILM-SHAPED CRYSTALS OF ORGANIC MATERIAL AS CAUSED BY APPLICATION OF THERMAL ENERGY THERETO RICOH COMPANY, LTD. (JP) 2000-07-18 US disclosed
US-6041157-A Environmentally sensitive compositions of matter based on 3H-fluoren-3-ylidenes and process for making same GOETZ FREDERICK JAMES (US) 2000-03-21 US disclosed
US-5185194-A Heat-mode recording medium RICOH COMPANY, LTD. (JP) 1993-02-09 US disclosed
US-4544505-A Preparation of halo-α-keto-carboxylic acids ETHYL CORPORATION (US) 1985-10-01 US disclosed
EP-0142571-A1 Preparation of bis-alpha-keto-carboxylic acids ETHYL CORPORATION (US) 1985-05-29 EP disclosed
WO-1985002180-A1 PREPARATION OF BIS-alpha-KETO-CARBOXYLIC ACIDS ETHYL CORPORATION (US) 1985-05-23 WO disclosed