Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7598138

COC(=O)CN(Cc1cc2cc(Cl)ccc2[nH]1)[C@@H]1CCN(Cc2ccc3c(N)ncnc3c2)C1=O.O=C(O)C(F)(F)F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
F10 P00742 13/20 0.54
SLC2A1 P11166 1/20 0.34
CYP51A1 Q16850 1/20 0.33
FNTA P49354 1/20 0.33
FNTB P49356 1/20 0.33
PGGT1B P53609 1/20 0.33
GPR183 P32249 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
DGAT1 O75907 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7537108 0.82 F10 (0.60) F10SLC2A1FNTAFNTBPGGT1B
Trifluoroacetic Acid SCHEMBL6224226 0.82 F10 (0.60) F10SLC2A1FNTAFNTBPGGT1B
Trifluoroacetic Acid SCHEMBL7537111 0.82 F10 (0.60) F10SLC2A1FNTAFNTBPGGT1B
SCHEMBL7407625 0.81 F10 (0.45) F10SLC2A1CYP51A1FNTAFNTB
Trifluoroacetic Acid SCHEMBL7537068 0.80 F10 (0.37) F10FNTAFNTBPGGT1BDGAT1
Trifluoroacetic Acid SCHEMBL7536990 0.78 F10 (0.37) F10DGAT1
Trifluoroacetic Acid SCHEMBL7409083 0.77 F10 (0.37) F10DGAT1
Trifluoroacetic Acid SCHEMBL7407446 0.77 F10 (0.52) F10FNTAFNTBPGGT1BSMN1; SMN2
Trifluoroacetic Acid SCHEMBL7407444 0.77 F10 (0.52) F10FNTAFNTBPGGT1BSMN1; SMN2
Trifluoroacetic Acid SCHEMBL7537062 0.76 F10 (0.37) F10DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1086099-A4 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARM PROD INC (US) 2002-01-02 EP disclosed
EP-1086099-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS Aventis Pharmaceuticals Products Inc. (US) 2001-03-28 EP disclosed
WO-1999062904-A1 SULFONIC ACID OR SULFONYLAMINO N-(HETEROARALKYL)-AZAHETEROCYCLYLAMIDE COMPOUNDS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 1999-12-09 WO disclosed