Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 12/20 | 0.76 |
| ▸ | CCKBR | P32239 | 6/20 | 0.54 |
| ▸ | CCKAR | P32238 | 2/20 | 0.54 |
| ▸ | PTH1R | Q03431 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591450 | 0.90 | BDKRB1 (0.76) | BDKRB1CCKBRCCKARPTH1R | |
| SCHEMBL1722848 | 0.82 | BDKRB1 (0.92) | BDKRB1CCKBR | |
| SCHEMBL7586803 | 0.78 | BDKRB1 (0.88) | BDKRB1CCKBR | |
| SCHEMBL9008722 | 0.77 | BDKRB1 (0.88) | BDKRB1CCKBR | |
| SCHEMBL7593227 | 0.77 | BDKRB1 (0.82) | BDKRB1CCKBR | |
| SCHEMBL7595345 | 0.76 | BDKRB1 (0.84) | BDKRB1CCKBR | |
| SCHEMBL9008762 | 0.76 | BDKRB1 (0.83) | BDKRB1CCKBR | |
| SCHEMBL7593661 | 0.76 | BDKRB1 (0.75) | BDKRB1CCKBR | |
| SCHEMBL7591109 | 0.73 | BDKRB1 (1.00) | BDKRB1CCKBR | |
| SCHEMBL7592838 | 0.72 | BDKRB1 (0.55) | BDKRB1CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002099388-A2 | BENZODIAZEPINE BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2002-12-12 | — | — | WO | disclosed |