Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099701 | 0.82 | KMT2A (0.63) | ABCB1SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7602308 | 0.80 | PPARG (0.56) | RAB9ANPC1MAPTKMT2AL3MBTL1 | |
| SCHEMBL10883891 | 0.77 | HDAC3 (0.60) | SMN1; SMN2RAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL7602706 | 0.77 | PPARG (0.50) | SMN1; SMN2RAB9AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6255775 | 0.77 | ABCB1 (0.50) | ABCB1SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL7598667 | 0.77 | ELANE (0.57) | ABCB1RAB9AALDH1A1NPC1KMT2A | |
| SCHEMBL14609920 | 0.77 | ABCB1 (0.47) | ABCB1SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL2099154 | 0.75 | ABCB1 (0.48) | ABCB1SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL12130470 | 0.74 | ABCB1 (0.45) | ABCB1SMN1; SMN2RAB9AALDH1A1NPC1 | |
| SCHEMBL1962745 | 0.74 | ESR1 (0.59) | ABCB1RAB9AALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020161007-A1 | Non-steroidal modulators of estrogen receptors | PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161007-A1 | Non-steroidal modulators of estrogen receptors | ESRRB, ESR2, ESRRG | ABCB1 1540/4885SMN1; SMN2 4570/4885RAB9A 4660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.