Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.75 |
| ▸ | LMNA | P02545 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 5/20 | 0.70 |
| ▸ | RAB9A | P51151 | 5/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420033 | 0.96 | TP53 (0.81) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL7598313 | 0.88 | TP53 (0.70) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL4650036 | 0.84 | TP53 (0.89) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL155002 | 0.83 | MAPT (1.00) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL13053140 | 0.81 | SMN1; SMN2 (0.89) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL18526177 | 0.81 | SMN1; SMN2 (0.60) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| Fluoride SCHEMBL7601046 | 0.81 | SMN1; SMN2 (0.60) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL2125047 | 0.79 | NPC1 (0.70) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL9642061 | 0.79 | MAPT (0.84) | TP53SMN1; SMN2LMNANPC1RAB9A | |
| SCHEMBL2792617 | 0.79 | NPC1 (0.70) | TP53SMN1; SMN2LMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747448-B1 | Rigidized monomethine cyanine dyes | UNIV CARNEGIE MELLON (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-0747448-A2 | Rigidized monomethine cyanine dyes | CARNEGIE-MELLON UNIVERSITY (US) | 1996-12-11 | — | — | EP | disclosed |