SCHEMBL7598320

SCHEMBL7598320

CC(C)(C)[Si](C)(C)Oc1cccc(C(=O)O)c1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.49
KDM4E B2RXH2 10/20 0.42
HSD17B10 Q99714 9/20 0.42
HPGD P15428 7/20 0.42
ALDH1A1 P00352 7/20 0.42
ESR1 P03372 1/20 0.41
ITGB3 P05106 1/20 0.41
ITGA2B P08514 1/20 0.41
HMGB1 P09429 1/20 0.41
TSHR P16473 1/20 0.41
GGT1 P19440 1/20 0.41
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
BLM P54132 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALOX15 P16050 2/20 0.40
HTT P42858 1/20 0.39
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6461382 0.92 MAPK1 (0.45) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL30594486 0.87 HTT (0.45) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL7557301 0.87 KDM4E (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL30872150 0.87 KDM4E (0.51) KDM4EHSD17B10HPGDALDH1A1ESR1
SCHEMBL31019409 0.86 PTGER1 (0.42) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL9070650 0.86 PTGER1 (0.42) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL9688332 0.86 KDM4E (0.46) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL1082757 0.85 ELANE (0.51) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL8303433 0.84 MAPK1 (0.40) MAPK1KDM4EHSD17B10HPGDALDH1A1
SCHEMBL14312138 0.82 MAPK1 (0.38) MAPK1KDM4EHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1222219-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA Northwestern University (US) 2002-07-17 EP disclosed
WO-2001021678-A1 SELF-ASSEMBLING COMPOUNDS AND USE OF THE SAME TO INDUCE ORDER IN ORGANIC MEDIA NORTHWESTERN UNIVERSITY (US) 2001-03-29 WO disclosed