Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 1.00 |
| ▸ | PDE4B | Q07343 | 7/20 | 1.00 |
| ▸ | PDE4C | Q08493 | 7/20 | 1.00 |
| ▸ | PDE4D | Q08499 | 7/20 | 1.00 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421101 | 0.91 | PDE4A (0.83) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7414911 | 0.88 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7423718 | 0.87 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL7420221 | 0.85 | PDE4A (0.73) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7424242 | 0.84 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7418296 | 0.83 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL7422581 | 0.82 | PDE4A (0.69) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL7425188 | 0.80 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPKM | |
| SCHEMBL7415562 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL7420778 | 0.79 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4DGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |