SCHEMBL7598405

SCHEMBL7598405

CCCCC1CCCC1[Si](Cl)(Cl)Cl

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
DPP4 P27487 1/20 0.36
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7593257 0.96 CYP1A2 (0.43) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL7599353 0.88 CA1 (0.43) NOS1NOS2CA1CA2CA4
SCHEMBL7590889 0.83 CA1 (0.48) CYP1A2NOS1NOS2CA1CA2
SCHEMBL7599113 0.82 CYP1A2 (0.40) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL7591334 0.79
SCHEMBL28598543 0.78 CYP1A2 (0.52) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL7597043 0.77 CYP1A2 (0.36) CYP1A2DPP4NOS1NOS2CA1
SCHEMBL7598163 0.76 CYP1A2 (0.35) CYP1A2DPP4NOS1NOS2
SCHEMBL7599301 0.74 CA1 (0.32) CA1CA2CA4
SCHEMBL28918175 0.73 CA1 (0.50) CYP1A2DPP4NOS1NOS2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0894802-B1 Silane compound NIPPON MITSUBISHI OIL CORP (JP) 2002-11-06 EP disclosed
EP-0894802-A2 Silane compound NIPPON OIL CO. LTD. (JP) 1999-02-03 EP disclosed