Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7586114 | 0.87 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL7946111 | 0.86 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL7584814 | 0.83 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL7598423 | 0.83 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL8321294 | 0.81 | EDNRB (0.71) | EDNRAEDNRB | |
| SCHEMBL7567452 | 0.81 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL7593718 | 0.81 | EDNRA (0.73) | EDNRAEDNRB | |
| SCHEMBL2678965 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL30057758 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7297093 | 0.81 | EDNRA (0.77) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856484-A | Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | claimed |
| EP-0768304-B1 | N-(Pyrimidinyl)-benzenesulfonamides as medicaments | HOFFMANN LA ROCHE (CH) | 2002-05-22 | — | — | EP | disclosed |
| US-5856484-A | Sulfonylaminopyrimidine carboxylic acid derivatives having endothelin inhibiting activity | HOFFMANN-LA ROCHE INC. (US) | 1999-01-05 | — | — | US | disclosed |
| EP-0768304-A1 | N-(Pyrimidinyl)-benzenesulfonamides as medicaments | F. HOFFMANN-LA ROCHE AG (CH) | 1997-04-16 | — | — | EP | disclosed |