Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7599443 | 0.92 | POLB (0.31) | POLB | |
| SCHEMBL7599000 | 0.90 | TMIGD3 (0.33) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL10344716 | 0.89 | TMIGD3 (0.33) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL7603323 | 0.89 | BRD4 (0.32) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL7599663 | 0.87 | SNCA (0.37) | TMIGD3ADORA3ADORA1 | |
| SCHEMBL7599048 | 0.86 | TMIGD3 (0.33) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL10821859 | 0.85 | TMIGD3 (0.34) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL7598036 | 0.84 | TYMS (0.38) | — | |
| SCHEMBL7599198 | 0.84 | TMIGD3 (0.36) | TMIGD3ADORA3ADORA2AADORA1POLB | |
| SCHEMBL2114276 | 0.83 | TMIGD3 (0.40) | TMIGD3ADORA3ADORA2AADORA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0135587-B2 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | SYNGENE INC (US) | 2002-12-18 | — | — | EP | disclosed |
| EP-0135587-B1 | DEFINED SEQUENCE SINGLE STRAND OLIGONUCLEOTIDES INCORPORATING REPORTER GROUPS, PROCESS FOR THE CHEMICAL SYNTHESIS THEREOF, AND NUCLEOSIDES USEFUL IN SUCH SYNTHESIS | SYNGENE, INC. (US) | 1990-05-02 | — | — | EP | disclosed |
| EP-0113860-B1 | PREPARATION PROCESS OF AZO DYES | BAYER AG (DE) | 1986-04-09 | — | — | EP | disclosed |