Sugi Predict

Sugi Predict / Compounds / Ammonia Solution, Strong

Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7599790

CC1(O)Cc2ccccc21.N

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.41
▸ MAPK1 P28482 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15868570 0.98 HTR2A (0.42) HTR2AMAPK1SMN1; SMN2LMNA
SCHEMBL14922392 0.81 PDK2 (0.41) HTR2ASMN1; SMN2LMNA
Ammonia Solution, Strong SCHEMBL10600738 0.78 KDM1A (0.44) MAPK1SMN1; SMN2LMNA
SCHEMBL9207434 0.78 KDM4E (0.39) HTR2AMAPK1SMN1; SMN2
SCHEMBL9207448 0.78 KDM4E (0.39) HTR2AMAPK1SMN1; SMN2
Ammonia Solution, Strong SCHEMBL3862601 0.76 HTR2A (0.43) HTR2A
SCHEMBL24262754 0.76 HTR2A (0.39) HTR2AMAPK1SMN1; SMN2LMNA
SCHEMBL3941515 0.76 KDM1A (0.46) MAPK1SMN1; SMN2LMNA
SCHEMBL2046731 0.76 MAPK1 (0.40) HTR2AMAPK1SMN1; SMN2
SCHEMBL19130582 0.76 KDM1A (0.46) MAPK1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6368573-B1 MEASURING MYOCARDIAL FUNCTION IN MAMMAL KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. 2002-04-09 — — US disclosed
US-4968697-A ADENOSINE-2 RECEPTOR AGONISTS CIBA-GEIGY CORPORATION (US) 1990-11-06 — — US disclosed