SCHEMBL7600448

SCHEMBL7600448

C=CCC(CC=C)CC(CC(=O)O)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 5/20 0.48
GRIK2 Q13002 5/20 0.48
CPA1 P15085 3/20 0.43
FOLH1 Q04609 2/20 0.42
ABCC4 O15439 1/20 0.36
MAPT P10636 1/20 0.36
CPB1 P15086 1/20 0.36
CPA3 P15088 1/20 0.36
CPB2 Q96IY4 1/20 0.36
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MME P08473 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114024 0.83 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL56402 0.83 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL24215021 0.83 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
Methane SCHEMBL27860390 0.81 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL30502843 0.81 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL8972060 0.81 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
Hydrochloric Acid SCHEMBL531801 0.81 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
Water SCHEMBL28049315 0.79 GRIK1 (0.52) GRIK1GRIK2CPA1FOLH1ABCC4
Methane SCHEMBL28007142 0.79 GRIK1 (0.52) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL6430077 0.78 ABCC4 (0.39) GRIK1GRIK2CPA1ABCC4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251122-A1 Process for the preparation of epsilon-Caprolactam DSM N.V. (NL) 2002-10-23 EP disclosed