Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.57 |
| ▸ | PGK1 | P00558 | 1/20 | 0.51 |
| ▸ | PGK2 | P07205 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835039 | 1.00 | ADORA2A (0.57) | ADORA2AADORA3ADORA2BADORA1PGK1 | |
| Formic Acid SCHEMBL6839110 | 0.96 | ADORA2A (0.56) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839844 | 0.93 | ADORA2A (0.56) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839334 | 0.92 | ADORA2A (0.54) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839796 | 0.90 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839715 | 0.90 | ADORA2A (0.55) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839042 | 0.90 | ADORA2A (0.72) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839112 | 0.90 | ADORA2A (0.50) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6839114 | 0.90 | ADORA2A (0.52) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL6835058 | 0.90 | ADORA2A (0.63) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051425-B1 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-30 | — | — | EP | claimed |