SCHEMBL7601297

SCHEMBL7601297

CCCCN1/C(=C/C=C2\CCC(/C=C/C3=[N+](CCCC)c4ccccc4C3(C)C)=C2S(=O)(=O)c2ccccc2)C(C)(C)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 5/20 0.51
PRMT5 O14744 1/20 0.44
CARM1 Q86X55 1/20 0.44
PRMT8 Q9NR22 1/20 0.44
HTR1A P08908 1/20 0.42
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPC1 O15118 1/20 0.41
USP2 O75604 1/20 0.41
S1PR2 O95136 1/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
ALPG P10696 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
XBP1 P17861 1/20 0.41
CRHBP P24387 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12237620 0.96 PRMT1 (0.51) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL12237585 0.93 PRMT1 (0.47) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL887480 0.92 PRMT1 (0.49) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL12237618 0.89 PRMT1 (0.46) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL12237587 0.89 PRMT1 (0.46) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL12237579 0.88 PRMT1 (0.45) PRMT1HTR1AMAPTMEN1HTT
SCHEMBL12237584 0.87 MEN1 (0.56) PRMT1HTR1AMAPTMEN1HTT
SCHEMBL14169853 0.87 FOLR1 (0.53) PRMT1HTR1AFOLR1PTPN1FOLH1
SCHEMBL18526580 0.86 PRMT1 (0.55) PRMT1PRMT5CARM1PRMT8HTR1A
SCHEMBL12414942 0.86 PRMT1 (0.45) PRMT1PRMT5CARM1PRMT8HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9069245-B2 Near-infrared absorptive layer-forming composition and multilayer film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-30 US disclosed
US-8722307-B2 Near-infrared absorptive layer-forming composition and multilayer film comprising near-infrared absorptive layer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-13 US disclosed
US-8323536-B2 Near-infrared absorbing dye, near-infrared absorptive film-forming composition, and near-infrared absorptive film SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-12-04 US disclosed
US-20120301828-A1 NEAR-INFRARED ABSORPTIVE LAYER-FORMING COMPOSITION AND MULTILAYER FILM COMPRISING NEAR-INFRARED ABSORPTIVE LAYER INTERNATIONAL BUSINESS MACHINES CORPORATION 2012-11-29 US disclosed
US-20120119171-A1 NEAR-INFRARED ABSORBING DYE, NEAR-INFRARED ABSORPTIVE FILM-FORMING COMPOSITION, AND NEAR-INFRARED ABSORPTIVE FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-05-17 US disclosed
US-20110262863-A1 NEAR-INFRARED ABSORPTIVE LAYER-FORMING COMPOSITION AND MULTILAYER FILM INTERNATIONAL BUSINESS MACHINES CORPORATION 2011-10-27 US disclosed
US-20110262862-A1 NEAR-INFRARED ABSORPTIVE LAYER-FORMING COMPOSITION AND MULTILAYER FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120119171-A1 NEAR-INFRARED ABSORBING DYE, NEAR-INFRARED ABSORPTIVE FILM-FORMING COMPOSITION, AND NEAR-INFRARED ABSORPTIVE FILM SLCO2A1, SLC39A3, SLCO2B1 PRMT1 652/4885PRMT5 2021/4885CARM1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.