⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724891 | 0.75 | — | — | |
| SCHEMBL2154646 | 0.75 | — | — | |
| SCHEMBL8052335 | 0.73 | — | — | |
| SCHEMBL11648324 | 0.73 | ESR1 (0.70) | — | |
| SCHEMBL40441 | 0.73 | ESR1 (0.70) | — | |
| SCHEMBL34204 | 0.73 | — | — | |
| SCHEMBL9361220 | 0.73 | CYP3A4 (0.53) | — | |
| SCHEMBL23243497 | 0.71 | TDP1 (0.50) | — | |
| SCHEMBL3962149 | 0.71 | ESR1 (0.75) | — | |
| SCHEMBL9217677 | 0.71 | TDP1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743059-B1 | Antibacterial oral composition for applying to dental implant areas | COLGATE PALMOLIVE CO (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6096293-A | APPLYING ORAL COMPOSITION CONTAINING 2,4-DI-TERT-BUTYL PHENOL TO TEETH | COLGATE-PALMOLIVE COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0852486-A2 | ANTIPLAQUE ORAL COMPOSITION | Colgate-Palmolive Company (US) | 1998-07-15 | — | — | EP | disclosed |
| US-5776435-A | DENTIFRICES | COLGATE-PALMOLIVE COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| US-5728756-A | BETA-STYRENEPHOSPHONIC ACID-VINYL PHOSPHONIC ACID COPOLYMER FOR ANTIPLAQUE | COLGATE PALMOLIVE COMPANY (US) | 1998-03-17 | — | — | US | disclosed |
| US-5686064-A | MIXTURE INCLUDES TETRAALKALI METAL POLYPHOSPHATE AND TRICLOSAN; DENTIFRICES | COLGATE PALMOLIVE COMPANY (US) | 1997-11-11 | — | — | US | disclosed |
| WO-1997010800-A2 | ANTIPLAQUE ORAL COMPOSITION | COLGATE-PALMOLIVE COMPANY (US) | 1997-03-27 | — | — | WO | disclosed |
| EP-0743059-A2 | Process for applying antibacterial oral composition to dental implant areas | Colgate-Palmolive Company (US) | 1996-11-20 | — | — | EP | disclosed |
| US-5575652-A | Process for applying antibacterial oral composition to dental implant areas | COLGATE PALMOLIVE COMPANY (US) | 1996-11-19 | — | — | US | disclosed |
| US-5538715-A | DENTIFRICES WITH ANTIPLAQUE AGENTS FOR MOUTHS WITH HUMECTANTS, SILICA POLISHES AND BACTERICIDES | COLGATE PALMOLIVE COMPANY (US) | 1996-07-23 | — | — | US | disclosed |
| US-5294431-A | Aqueous vehicle, noncationic bactericide, surfactant, flavoring oil, alcohol and a bactericide promoter enhancing delivery and adhesion; phosphate-free | COLGATE-PALMOLIVE CO. (US) | 1994-03-15 | — | — | US | disclosed |
| US-5292526-A | Macroemulsion of non-cationic antibacterial agent | COLGATE-PALMOLIVE CO. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5288480-A | Antiplaque antibacterial oral composition | COLGATE-PALMOLIVE CO. (US) | 1994-02-22 | — | — | US | disclosed |
| US-5275805-A | Inhibitors of plaque in mouths with mixtures of salicylanilide and nonionic surfactants | COLGATE-PALMOLIVE CO. | 1994-01-04 | — | — | US | disclosed |
| US-5192530-A | Solubilizer, enhancing agent to aid retention, and delivery enhancement | COLGATE-PALMOLIVE COMPANY (US) | 1993-03-09 | — | — | US | disclosed |
| US-5192531-A | Triclosan as a water insoluble noncationic additive for dentifrices | COLGATE-PALMOLIVE COMPANY (US) | 1993-03-09 | — | — | US | disclosed |
| US-5188821-A | ANTIBACTERIAL ANTIPLAQUE ORAL COMPOSITION MOUTHWASH OR LIQUID DENTIFRICE | COLGATE-PALMOLIVE COMPANY (US) | 1993-02-23 | — | — | US | disclosed |
| US-5180578-A | Adhesion to oral surfaces | COLGATE-PALMOLIVE COMPANY (US) | 1993-01-19 | — | — | US | disclosed |
| US-5178851-A | Dentifrices treatment with triclosan and carriers | COLGATE-PALMOLIVE COMPANY (US) | 1993-01-12 | — | — | US | disclosed |
| US-5032386-A | Dentistry | COLGATE-PALMOLIVE COMPANY (US) | 1991-07-16 | — | — | US | disclosed |