Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864659 | 0.98 | KCNH2 (0.48) | KCNH2GPR84HCAR2HCAR3PTGS2 | |
| SCHEMBL30191371 | 0.98 | KCNH2 (0.48) | KCNH2GPR84HCAR2HCAR3PTGS2 | |
| SCHEMBL30078849 | 0.79 | KCNH2 (0.48) | KCNH2GPR84HCAR2ALDH1A1 | |
| SCHEMBL990250 | 0.79 | KCNH2 (0.48) | KCNH2GPR84HCAR2ALDH1A1 | |
| SCHEMBL7701413 | 0.78 | KCNH2 (0.47) | KCNH2GPR84HCAR2HCAR3ALDH1A1 | |
| SCHEMBL1063754 | 0.78 | KCNH2 (0.47) | KCNH2GPR84ALDH1A1 | |
| SCHEMBL278227 | 0.78 | KCNH2 (0.43) | KCNH2GPR84HCAR2HCAR3ALDH1A1 | |
| SCHEMBL9966143 | 0.77 | — | — | |
| SCHEMBL10697416 | 0.77 | KCNH2 (0.50) | KCNH2GPR84ALDH1A1 | |
| SCHEMBL9817100 | 0.77 | KCNH2 (0.50) | KCNH2GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244635-A2 | 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001049668-A2 | 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLES AND USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | WO | claimed |
| EP-1244635-A2 | 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLE | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001049668-A2 | 4-ARYL-1-DIFLUOROMETHOXYIMIDAZOLES AND USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-12 | — | — | WO | disclosed |