Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6839161 | 1.00 | ADORA2A (0.51) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL7596792 | 0.99 | ADORA2A (0.52) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL6839295 | 0.99 | ADORA2A (0.52) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL7596797 | 0.99 | ADORA2A (0.52) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL6839061 | 0.91 | ADORA2A (0.55) | ADORA2AADORA3 | |
| SCHEMBL7601697 | 0.89 | ADORA2A (0.53) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL6835017 | 0.89 | ADORA2A (0.53) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL7598658 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL7598650 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3PGK1PGK2 | |
| SCHEMBL6838990 | 0.88 | ADORA2A (0.54) | ADORA2AADORA3PGK1PGK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051425-B1 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-10-30 | — | — | EP | claimed |