SCHEMBL76021

SCHEMBL76021

CC(=O)OC(C)C(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76020 1.00
SCHEMBL1136637 1.00
SCHEMBL31468276 0.91 TSHR (0.44)
SCHEMBL31468268 0.91 TSHR (0.44)
SCHEMBL6411139 0.79 TSHR (0.48)
SCHEMBL14997322 0.79
SCHEMBL359717 0.77
SCHEMBL16316794 0.77
SCHEMBL18225 0.77
SCHEMBL25178226 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 715 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4172139-B1 PROCESS FOR THE PREPARATION OF IOPAMIDOL GE HEALTHCARE AS (NO) 2025-09-24 EP claimed
CN-120136700-A Synthesis method of L-acetoxy propionyl chloride 连云港百裕生物科技有限公司 2025-06-13 CN claimed
EP-4313934-B1 INDUSTRIAL SYNTHESIS OF SERINOL BRACCO IMAGING SPA (IT) 2025-05-07 EP claimed
WO-2025073833-A1 OPTIMIZED PROCESS FOR THE PREPARATION OF IOPAMIDOL BRACCO IMAGING SPA (IT) 2025-04-10 WO claimed
EP-4534526-A1 OPTIMIZED PROCESS FOR THE PREPARATION OF IOPAMIDOL Bracco Imaging SPA (IT) 2025-04-09 EP claimed
US-20240199530-A1 INDUSTRIAL SYNTHESIS OF SERINOL BRACCO IMAGING S.P.A. (IT) 2024-06-20 US claimed
CN-115010617-B Preparation method of iopamidol 安徽普利药业有限公司 2024-06-11 CN claimed
EP-4313934-A1 INDUSTRIAL SYNTHESIS OF SERINOL Bracco Imaging SPA (IT) 2024-02-07 EP claimed
CN-116854610-A Process for the preparation of impurities K and H of iopamidol and intermediates thereof 江苏宇田医药有限公司 2023-10-10 CN claimed
CN-116745260-A Industrial synthesis of serinol 伯拉考成像股份公司 2023-09-12 CN claimed
US-5672735-A 5-((ACETYLOXY)-1-OXOPROPYL)AMINO)-2,4,6-TRIIODO-1,3-BENZENEDI CARBONYL CHLORIDE BY REACTING 5-AMINO-2,4,6-TRIIODOBENZENE DICARBONYL CHLORIDE WITH THE PROPIONYL CHLORIDE COMPOUND USING AN APROTIC DIPOLAR SOLVENT AND HALOHYDRIC ACID CATALYST FRUCTAMINE S.P.A. (IT) 1997-09-30 US claimed
US-5580993-A Process for the preparation of iopamidol and 5-amino-2,2-dialkyl-1,3-dioxanes ZAMBON GROUP S.P.A. (IT) 1996-12-03 US claimed
EP-0619744-A4 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS. MALLINCKRODT MEDICAL INC (US) 1995-02-08 EP claimed
US-5362905-A Process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride ZAMBON GROUP S.P.A. (IT) 1994-11-08 US claimed
EP-0619744-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1994-10-19 EP claimed
WO-1994005337-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1994-03-17 WO claimed
WO-1993010825-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT MEDICAL, INC. (US) 1993-06-10 WO claimed
US-5191120-A Process for preparing nonionic X-ray contrast agents MALLINCKRODT MEDICAL, INC. (US) 1993-03-02 US claimed
EP-0504266-A1 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1992-09-23 EP claimed
WO-1991009007-A2 NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS MALLINCKRODT, INC. (US) 1991-06-27 WO claimed