Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | XBP1 | P17861 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | ACACA | Q13085 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237463 | 0.93 | HPGD (0.50) | HPGDXBP1LMNAMAPTUSP2 | |
| SCHEMBL237464 | 0.85 | HPGD (0.49) | HPGDXBP1LMNAMAPTUSP2 | |
| SCHEMBL246848 | 0.85 | FABP3 (0.50) | LMNAMAPTMAPK1HTTPTGS2 | |
| SCHEMBL361868 | 0.83 | HPGD (0.55) | HPGDXBP1LMNAMAPTACACB | |
| SCHEMBL17697669 | 0.82 | FABP3 (0.48) | LMNAMEN1KMT2AMAPK1HTT | |
| SCHEMBL30462994 | 0.79 | FFAR4 (0.50) | LMNAMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7803935 | 0.79 | PPARA (0.41) | HPGDXBP1LMNAKMT2ATDP1 | |
| SCHEMBL236809 | 0.79 | FFAR4 (0.55) | LMNAACACBACACAMAPK1HTT | |
| SCHEMBL236822 | 0.78 | FABP3 (0.53) | HPGDLMNAMAPK1HTTRAB9A | |
| SCHEMBL237465 | 0.78 | SMN1; SMN2 (0.51) | HPGDXBP1LMNAMAPTACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482877-B2 | MELT PROCESSABILITY; MIXTURE WITH PHOSPHOROUS ACID, SULFUR COMPOUND AND FATTY ESTER | GENERAL ELECTRIC COMPANY | 2002-11-19 | — | — | US | disclosed |
| EP-1156078-A1 | Polycarbonate resin composition for optical use | GENERAL ELECTRIC COMPANY (US) | 2001-11-21 | — | — | EP | disclosed |
| US-20010041759-A1 | Polycarbonate resin composition for optical use | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2001-11-15 | — | — | US | disclosed |
| US-6271290-B1 | OPTICAL POLYMERS PREPARED BY MELT CONDENSATION | GENERAL ELECTRIC COMPANY | 2001-08-07 | — | — | US | disclosed |