Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123637 | 0.79 | MAPT (0.52) | KDM4EHRH3HRH2HRH1MAPT | |
| SCHEMBL13316306 | 0.78 | POLB (0.53) | KDM4EHRH3HRH2HRH1HSD17B10 | |
| SCHEMBL27280854 | 0.78 | KDM4E (0.56) | KDM4EHRH3HSD17B10MEN1KMT2A | |
| SCHEMBL21227464 | 0.78 | POLB (0.53) | KDM4EHRH3HRH2HRH1HSD17B10 | |
| SCHEMBL14654955 | 0.78 | POLB (0.53) | KDM4EHRH3HRH2HRH1HSD17B10 | |
| SCHEMBL7603518 | 0.78 | KDM4E (0.51) | KDM4EHRH3HRH2HRH1 | |
| SCHEMBL12424438 | 0.77 | POLB (0.52) | KDM4EHRH3HRH2HRH1HSD17B10 | |
| SCHEMBL7602980 | 0.76 | KDM4E (0.58) | KDM4EHRH3HSD17B10MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL7603171 | 0.76 | KDM4E (0.50) | KDM4EHRH3HRH2HRH1 | |
| SCHEMBL12449688 | 0.76 | KDM4E (0.61) | KDM4EHSD17B10MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962447-B1 | Process for the preparation of secondary or tertiary 2-methyl-1,5-pentanediamines | BASF AG (DE) | 2002-12-18 | — | — | EP | disclosed |
| EP-0822933-B1 | PROCESS FOR PRODUCING PIPERIDINOPENTANAMINES | LONZA AG (CH) | 2001-10-24 | — | — | EP | disclosed |
| EP-1092713-A2 | Piperidinopentanamines and their use as catalysts in the preparation of urethanes | LONZA AG (CH) | 2001-04-18 | — | — | EP | disclosed |
| US-6198002-B1 | REACTING 2-METHYLGLUTARONITRILE WITH PRIMARY OR SECONDARY AMINE AND HYDROGEN IN PRESENCE OF OXIDIC SUPPORTED CATALYST COMPRISING ONE OR MORE NOBLE METALS WHICH HAS BEEN TREATED WITH HYDROGEN | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| US-6080865-A | A POLYMERIZATION CATALYSTS IN THE PRODUCTION OF POLYURETHANES; A REACTION PRODUCT OF THE 2-METHYLGLUTARONITRILE WITH HYDROGEN | LONZA AG (CH) | 2000-06-27 | — | — | US | disclosed |
| EP-0962447-A2 | Process for the preparation of secondary or tertiary 2-methyl-1,5-pentanediamines | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-08 | — | — | EP | disclosed |
| EP-0759914-B1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1998-09-23 | — | — | EP | disclosed |
| EP-0822933-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1998-02-11 | — | — | EP | disclosed |
| US-5698607-A | Tertiary diamine, its use as catalyst, and process for preparing tertiary diamines | LONZA AG (CH) | 1997-12-16 | — | — | US | disclosed |
| EP-0759914-A1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996033986-A1 | PIPERIDINOPENTANAMINES, PROCESS FOR PRODUCING THEM AND THEIR USE AS A CATALYST FOR PRODUCING URETHANES | LONZA AG (CH) | 1996-10-31 | — | — | WO | disclosed |
| WO-1995030666-A1 | TERTIARY DIAMINE, ITS USE AS CATALYST AND METHOD FOR PREPARATION OF TERTIARY DIAMINES | LONZA AG (CH) | 1995-11-16 | — | — | WO | disclosed |