Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | GRM5 | P41594 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159662 | 0.86 | MAOB (0.73) | MAOBCYP19A1MAPTMAOAPSMB5 | |
| SCHEMBL1895399 | 0.81 | MAOB (1.00) | MAOBCYP19A1MAPTCYP3A4AR | |
| SCHEMBL131515 | 0.81 | MAOB (1.00) | MAOBCYP19A1MAPTCYP3A4AR | |
| SCHEMBL27474119 | 0.81 | KMT2A (1.00) | MAOBHSD17B10MEN1MAPTKMT2A | |
| SCHEMBL20412502 | 0.81 | AR (0.61) | MAOBCYP19A1HSD17B10MAPTMAOA | |
| SCHEMBL27718675 | 0.80 | MAOB (0.70) | MAOBCYP19A1HSD17B10MAOAPSMB5 | |
| SCHEMBL2399200 | 0.80 | MAOB (0.68) | MAOBCYP19A1CYP3A4 | |
| SCHEMBL10360803 | 0.79 | MAOB (0.70) | MAOBCYP19A1HSD17B10MAPTMAOA | |
| SCHEMBL17708746 | 0.79 | CYP19A1 (0.77) | MAOBCYP19A1MAPTCYP3A4AR | |
| SCHEMBL17708749 | 0.79 | CYP19A1 (0.77) | MAOBCYP19A1MAPTCYP3A4AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413998-B1 | BONE REGENERATION | OSTEOSCREEN, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6008208-A | Compositions and methods for treating bone deficit conditions | OSTEOSCREEN, INC. (US) | 1999-12-28 | — | — | US | disclosed |