SCHEMBL7604209

SCHEMBL7604209

COC(=O)COCCN1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TLR8 Q9NR97 1/20 0.43
ALDH1A1 P00352 1/20 0.42
EPHX2 P34913 8/20 0.42
ACKR3 P25106 3/20 0.42
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31286711 0.90 SCN9A (0.44) SMN1; SMN2TLR8EPHX2
SCHEMBL20572924 0.89 USP2 (0.43) USP2SMN1; SMN2TLR8EPHX2ACKR3
SCHEMBL20211851 0.86 TLR8 (0.43) USP2SMN1; SMN2TLR8ACKR3CHRM2
SCHEMBL30097282 0.86 CYP2D6 (0.43) USP2SMN1; SMN2ALDH1A1EPHX2
SCHEMBL20211861 0.85 USP2 (0.45) USP2SMN1; SMN2TLR8EPHX2ACKR3
SCHEMBL21068826 0.84 TLR8 (0.46) USP2SMN1; SMN2TLR8ALDH1A1EPHX2
SCHEMBL22262696 0.84 USP2 (0.44) USP2SMN1; SMN2TLR8ALDH1A1EPHX2
SCHEMBL6661328 0.84 USP2 (0.44) USP2SMN1; SMN2TLR8ALDH1A1EPHX2
SCHEMBL15352136 0.84 USP2 (0.44) USP2SMN1; SMN2TLR8ALDH1A1EPHX2
SCHEMBL7605519 0.84 TLR8 (0.46) USP2SMN1; SMN2TLR8EPHX2ACKR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0927173-B1 SUBSTITUTED [2-(1-PIPERAZINYL)ETHOXY]METHYL UCB SA (BE) 2002-06-12 EP claimed
CN-1072661-C Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 2001-10-10 CN claimed
US-6140501-A CHEMICAL INTERMEDIATES UCB, S.A. (BE) 2000-10-31 US claimed
CN-1215395-A Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 1999-04-28 CN claimed
EP-4747248-A1 COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION Institute of Cancer Research: Royal Cancer Hospital (The) (GB) 2026-05-27 EP disclosed
WO-2025022093-A1 COMPOUNDS FOR USE IN A METHOD OF TARGETED PROTEIN DEGRADATION THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) 2025-01-30 WO disclosed
CN-1072661-C Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 2001-10-10 CN disclosed
US-6255487-B1 PREPARING 2-(2-(4-((4-CHLOROPHENYL)PHENYLMETHYL)-1-PIPER-AZINYL)ETHOXY)ACETIC ACID VIA REACTING SUBSTITUTED (2-((1-PIPERAZINYL)ETHOXY)METHYL COMPOUND WITH A DIPHENYLMETHYL HALIDE, THEN HYDROLYZING IN ALCOHOLIC MEDIUM WITH ACID/BASE UCB, S.A. (BE) 2001-07-03 US disclosed
US-6140501-A CHEMICAL INTERMEDIATES UCB, S.A. (BE) 2000-10-31 US disclosed
CN-1215395-A Novel substituted [2-(1-piperazinyl) ethoxy] methyl UCB SA (BE) 1999-04-28 CN disclosed