Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053110 | 0.95 | FOLH1 (0.53) | FOLH1GRM3 | |
| SCHEMBL5054569 | 0.95 | FOLH1 (0.53) | FOLH1GRM3 | |
| SCHEMBL5059943 | 0.95 | FOLH1 (0.53) | FOLH1GRM3 | |
| SCHEMBL5053188 | 0.94 | FOLH1 (0.54) | FOLH1GRM3 | |
| SCHEMBL5051342 | 0.90 | FOLH1 (0.59) | FOLH1GRM3 | |
| SCHEMBL7604484 | 0.85 | FOLH1 (0.43) | FOLH1CPB2 | |
| SCHEMBL1373664 | 0.85 | GRM3 (0.65) | FOLH1GRM3 | |
| SCHEMBL5060019 | 0.84 | FOLH1 (0.66) | FOLH1GRM3 | |
| SCHEMBL5051180 | 0.84 | FOLH1 (0.66) | FOLH1GRM3 | |
| SCHEMBL5053298 | 0.84 | FOLH1 (0.66) | FOLH1GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002515040-A | — | — | 2002-05-21 | — | — | JP | claimed |
| EP-0954295-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1999-11-10 | — | — | EP | claimed |
| WO-1997048409-A1 | METHODS OF CANCER TREATMENT USING NAALADASE INHIBITORS | GUILFORD PHARMACEUTICALS INC. (US) | 1997-12-24 | — | — | WO | claimed |