Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 19/20 | 0.62 |
| ▸ | MTTP | P55157 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7605100 | 1.00 | NPY2R (0.62) | NPY2RMTTPKDM4EMEN1ALDH1A1 | |
| SCHEMBL14537950 | 1.00 | NPY2R (0.62) | NPY2RMTTPKDM4EMEN1ALDH1A1 | |
| SCHEMBL7603935 | 0.89 | NPY2R (0.58) | NPY2RMTTPKDM4EMEN1ALDH1A1 | |
| SCHEMBL13890091 | 0.87 | NPY2R (0.59) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL13873633 | 0.87 | NPY2R (0.59) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7600303 | 0.87 | NPY2R (0.62) | NPY2RMTTPALDH1A1HPGD | |
| SCHEMBL5081650 | 0.84 | NPY2R (0.75) | NPY2RMTTP | |
| SCHEMBL13873603 | 0.82 | NPY2R (0.57) | NPY2RKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL14537895 | 0.80 | NPY2R (0.80) | NPY2R | |
| SCHEMBL7607274 | 0.80 | NPY2R (0.80) | NPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183239-B2 | Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-22 | — | — | US | disclosed |