Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.78 |
| ▸ | BACE2 | Q9Y5Z0 | 5/20 | 0.78 |
| ▸ | CTSD | P07339 | 4/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344920 | 1.00 | BACE1 (0.78) | BACE1BACE2CTSD | |
| SCHEMBL5348605 | 0.93 | BACE1 (0.88) | BACE1BACE2CTSD | |
| SCHEMBL5354471 | 0.92 | BACE1 (0.87) | BACE1BACE2CTSD | |
| SCHEMBL3350930 | 0.92 | BACE1 (0.86) | BACE1BACE2CTSD | |
| SCHEMBL5346831 | 0.92 | BACE1 (0.85) | BACE1BACE2CTSD | |
| SCHEMBL3351026 | 0.89 | BACE1 (0.76) | BACE1BACE2CTSD | |
| SCHEMBL5376347 | 0.88 | BACE1 (0.65) | BACE1BACE2CTSD | |
| SCHEMBL3904992 | 0.88 | BACE1 (0.88) | BACE1BACE2CTSD | |
| SCHEMBL3349454 | 0.87 | BACE1 (1.00) | BACE1BACE2CTSD | |
| SCHEMBL3348990 | 0.87 | BACE1 (1.00) | BACE1BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PHARMACIA & UPJOHN COMPANY | 2002-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128255-A1 | Compounds to treat alzheimer's disease | PSEN2, PSEN1, APP | BACE1 4/4885BACE2 9/4885CTSD 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.