Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 15/20 | 0.51 |
| ▸ | F10 | P00742 | 4/20 | 0.51 |
| ▸ | CTRC | Q99895 | 4/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608549 | 0.94 | F2 (0.53) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866351 | 0.94 | F2 (0.54) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866158 | 0.92 | F2 (0.52) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866246 | 0.88 | F2 (0.51) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866097 | 0.88 | F2 (0.51) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL7611244 | 0.87 | F2 (0.51) | F2F10CTRCCACNA1BPRSS2 | |
| Hydrochloric Acid SCHEMBL5866102 | 0.87 | F2 (0.50) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866271 | 0.87 | F2 (0.50) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866121 | 0.86 | F2 (0.49) | F2F10CTRCCACNA1BPRSS2 | |
| SCHEMBL5866114 | 0.86 | F2 (0.49) | F2F10CTRCCACNA1BPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917528-B1 | NEW AMIDINO DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS | ASTRAZENECA AB (SE) | 2002-09-18 | — | — | EP | claimed |