Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.46 |
| ▸ | BCHE | P06276 | 8/20 | 0.45 |
| ▸ | ACHE | P22303 | 7/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7606822 | 1.00 | SLC2A1 (0.59) | SLC2A1CA12CA9CA1CA2 | |
| SCHEMBL12531209 | 0.90 | SLC2A1 (0.62) | SLC2A1MCHR1BCHEACHEHTR2C | |
| SCHEMBL7616324 | 0.90 | SLC2A1 (0.68) | SLC2A1MCHR1BCHEACHEHTR2C | |
| SCHEMBL7607742 | 0.90 | SLC2A1 (0.68) | SLC2A1MCHR1BCHEACHEHTR2C | |
| SCHEMBL7617202 | 0.89 | SLC2A1 (0.63) | SLC2A1CA12CA9CA1CA2 | |
| SCHEMBL7617198 | 0.89 | SLC2A1 (0.63) | SLC2A1CA12CA9CA1CA2 | |
| SCHEMBL7606829 | 0.87 | BCHE (0.50) | SLC2A1CA12CA9CA1CA2 | |
| SCHEMBL7612344 | 0.86 | SLC2A1 (0.63) | SLC2A1MCHR1BCHEACHEHTR2C | |
| SCHEMBL7612340 | 0.86 | SLC2A1 (0.63) | SLC2A1MCHR1BCHEACHEHTR2C | |
| SCHEMBL7616800 | 0.85 | SLC2A1 (0.62) | SLC2A1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |