SCHEMBL7606903

SCHEMBL7606903

O=C(O)c1ccc2c(c1)nc1c3ccc4c5ccc6c(=O)n7c8cc(C(=O)O)ccc8nc7c7ccc(c8ccc(c(=O)n21)c3c48)c5c67

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.53
MAPT P10636 5/20 0.53
MEN1 O00255 4/20 0.53
CAMKK1 Q8N5S9 2/20 0.53
CAMKK2 Q96RR4 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 1/20 0.53
CYP2C9 P11712 1/20 0.53
CASP1 P29466 1/20 0.53
CYP2C19 P33261 1/20 0.53
CASP7 P55210 1/20 0.53
CSNK2A2 P19784 1/20 0.50
CSNK2B P67870 1/20 0.50
CSNK2A1 P68400 1/20 0.50
PIM3 Q86V86 1/20 0.50
DYRK2 Q92630 1/20 0.50
MKNK1 Q9BUB5 1/20 0.50
PIM2 Q9P1W9 1/20 0.50
AHR P35869 1/20 0.47
BCL2 P10415 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7604980 1.00 KMT2A (0.53) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL7606910 0.95 KMT2A (0.54) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL7603789 0.95 KMT2A (0.54) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL7607043 0.95 KMT2A (0.54) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL7607038 0.95 KMT2A (0.54) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL14502336 0.94 KMT2A (0.55) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL12036943 0.94 KMT2A (0.55) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL7606945 0.92 MAPT (0.64) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL12593638 0.91 KMT2A (0.55) KMT2AMAPTMEN1CAMKK1CAMKK2
SCHEMBL13511561 0.90 KMT2A (0.47) KMT2AMAPTMEN1CAMKK1CAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8222074-B2 Anisotropic semiconductor film and method of production thereof CARBEN SEMICON LIMITED (CY) 2012-07-17 US disclosed
US-20120122274-A1 ANISOTROPIC SEMICONDUCTOR FILM AND METHOD OF PRODUCTION THEREOF CARBEN SEMICON LIMITED (CY) 2012-05-17 US disclosed
US-8124966-B2 Anisotropic semiconductor film and method of production thereof CARBEN SEMICON LIMITED (CY) 2012-02-28 US disclosed
US-8124966-B2 Anisotropic semiconductor film and method of production thereof CARBEN SEMICON LIMITED (CY) 2012-02-28 US disclosed
US-20100224998-A1 Integrated Circuit with Ribtan Interconnects CARBEN SEMICON LIMITED (CY) 2010-09-09 US disclosed
US-20100224998-A1 Integrated Circuit with Ribtan Interconnects CARBEN SEMICON LIMITED (CY) 2010-09-09 US disclosed
US-20100173134-A1 Film and Device Using Layer Based on Ribtan Material CARBEN SEMICON LIMITED (CY) 2010-07-08 US disclosed
US-20100173134-A1 Film and Device Using Layer Based on Ribtan Material CARBEN SEMICON LIMITED (CY) 2010-07-08 US disclosed
US-20100038629-A1 Anisotropic Semiconductor Film and Method of Production Thereof CARBEN SEMICON LIMITED (CY) 2010-02-18 US disclosed
US-20100038629-A1 Anisotropic Semiconductor Film and Method of Production Thereof CARBEN SEMICON LIMITED (CY) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100173134-A1 Film and Device Using Layer Based on Ribtan Material RNF213, PRDM9, RNF10 KMT2A 1471/4885MAPT 1506/4885MEN1 2792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.