Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.39 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10874504 | 0.87 | FFAR3 (0.47) | SLC1A3SLC1A2SLC1A1ALOX15GRIK1 | |
| Carbamic Acid SCHEMBL9280663 | 0.87 | — | — | |
| Acetic Acid SCHEMBL19350438 | 0.87 | FFAR3 (0.47) | SLC1A3SLC1A2SLC1A1ALOX15GRIK1 | |
| Acetic Acid SCHEMBL242246 | 0.87 | FFAR3 (0.47) | SLC1A3SLC1A2SLC1A1ALOX15GRIK1 | |
| Acetic Acid SCHEMBL6280777 | 0.87 | — | — | |
| Propionic Acid SCHEMBL30448445 | 0.84 | FFAR3 (0.62) | SLC1A3SLC1A2SLC1A1GRIK1GRIA4 | |
| Acetic Acid SCHEMBL5351332 | 0.84 | FFAR3 (0.44) | SLC1A3SLC1A2SLC1A1GRIK1GRIA4 | |
| Acetic Acid SCHEMBL9737099 | 0.84 | FFAR3 (0.44) | SLC1A3SLC1A2SLC1A1GRIK1GRIA4 | |
| Acetic Acid SCHEMBL9644947 | 0.84 | FFAR3 (0.44) | SLC1A3SLC1A2SLC1A1GRIK1GRIA4 | |
| Propionic Acid SCHEMBL28047135 | 0.84 | FFAR3 (0.62) | SLC1A3SLC1A2SLC1A1GRIK1GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263718-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | AstraZeneca AB (SE) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001062721-A1 | NOVEL USE OF PHENYLHETEROALKYLAMINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-08-30 | — | — | WO | disclosed |