Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.67 |
| ▸ | CASP1 | P29466 | 5/20 | 0.67 |
| ▸ | CASP7 | P55210 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.64 |
| ▸ | TP53 | P04637 | 9/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607598 | 0.96 | MAPT (0.67) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL7609382 | 0.91 | MAPT (0.70) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL4648874 | 0.88 | ABCG2 (0.82) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL14708632 | 0.84 | MAPT (0.61) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL8424729 | 0.82 | MAPT (0.73) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL30667444 | 0.81 | MAPT (1.00) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL5138212 | 0.81 | MAPT (1.00) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL25235022 | 0.80 | ABCB1 (0.79) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL30397364 | 0.80 | ABCB1 (0.79) | MAPTKDM4ECYP3A4CASP1CASP7 | |
| SCHEMBL1422017 | 0.80 | MAPT (0.76) | MAPTKDM4ECYP3A4CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915864-B1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARM CO LTD (KR) | 2002-09-04 | — | — | EP | disclosed |