Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3533303 | 0.81 | HRH3 (0.64) | HRH3ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL1380900 | 0.78 | HRH3 (0.80) | HRH3ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL3531356 | 0.78 | HRH3 (0.55) | HRH3ALDH1A1LMNAHPGDADORA2A | |
| SCHEMBL1381406 | 0.78 | HRH3 (0.81) | HRH3ALDH1A1LMNAHPGD | |
| SCHEMBL3540839 | 0.76 | HRH3 (0.73) | HRH3ALDH1A1LMNAADORA2AALOX15 | |
| SCHEMBL3533474 | 0.76 | HRH3 (0.66) | HRH3ALDH1A1LMNAHPGDNPC1 | |
| SCHEMBL3531033 | 0.73 | HRH3 (0.67) | HRH3ALDH1A1LMNANPC1MEN1 | |
| SCHEMBL3533357 | 0.72 | HRH3 (0.51) | HRH3ALDH1A1LMNANPC1MEN1 | |
| SCHEMBL3534692 | 0.71 | HRH3 (0.79) | HRH3ALDH1A1LMNANPC1MEN1 | |
| SCHEMBL3539979 | 0.69 | HRH3 (0.57) | HRH3ALDH1A1LMNAADORA2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198237-A1 | Heterocyclic compounds | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2002-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198237-A1 | Heterocyclic compounds | HRH2, HRH4, HRH1 | HRH3 4/4885ALDH1A1 1526/4885LMNA 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.