SCHEMBL7607657

SCHEMBL7607657

CCCCC(CC)COP(=S)(OCC(CC)CCCC)SC(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
TSHR P16473 4/20 0.39
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 7/20 0.37
CA2 P00918 3/20 0.35
RECQL P46063 1/20 0.33
LMNA P02545 2/20 0.32
MMP9 P14780 1/20 0.32
MMP8 P22894 1/20 0.32
MMP14 P50281 1/20 0.32
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15178626 0.84 CYP3A4 (0.59) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL5463291 0.84 CYP3A4 (0.51) CYP3A4L3MBTL1TSHRTDP1ATM
Zinc Ion SCHEMBL1395686 0.83 CYP3A4 (0.50) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL5164929 0.83 CYP3A4 (0.50) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL29435916 0.81 CYP3A4 (0.56) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL9306250 0.78 CYP3A4 (0.49) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL9306765 0.78 CYP3A4 (0.49) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL284454 0.78 CYP3A4 (0.66) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL16420191 0.77 CYP3A4 (0.63) CYP3A4L3MBTL1TSHRTDP1ATM
SCHEMBL5164921 0.76 CYP3A4 (0.58) CYP3A4L3MBTL1TSHRTDP1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0962518-B1 Grease compositions LUBRIZOL CORP (US) 2002-12-18 EP disclosed
US-6100226-A Simple metal grease compositions THE LUBRIZOL CORPORATION (US) 2000-08-08 US disclosed
EP-0651043-B1 Grease compositions LUBRIZOL CORP (US) 2000-05-24 EP disclosed
EP-0962518-A1 Grease compositions The Lubrizol Corporation (US) 1999-12-08 EP disclosed
EP-0580335-B1 Grease compositions LUBRIZOL CORP (US) 1997-09-10 EP disclosed
EP-0580331-B1 Grease compositions LUBRIZOL CORP (US) 1997-09-10 EP disclosed
EP-0651043-A2 Grease compositions The Lubrizol Corporation (US) 1995-05-03 EP disclosed
US-5362409-A Thiophosphorus acid ester THE LUBRIZOL CORPORATION (US) 1994-11-08 US disclosed
EP-0580335-A1 Grease compositions The Lubrizol Corporation (US) 1994-01-26 EP disclosed
EP-0580331-A1 Grease compositions The Lubrizol Corporation (US) 1994-01-26 EP disclosed
US-5256320-A Overbased metal salts, thiophosphates, and phosphites blended THE LUBRIZOL CORPORATION (US) 1993-10-26 US disclosed
US-5256321-A Grease compositions THE LUBRIZOL CORPORATION (US) 1993-10-26 US disclosed