Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.61 |
| ▸ | VDR | P11473 | 3/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | CASP7 | P55210 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MDM4 | O15151 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552067 | 0.92 | GPBAR1 (0.72) | GPBAR1HIF1AVDRCYP2C9USP2 | |
| SCHEMBL7606272 | 0.89 | GPBAR1 (0.70) | GPBAR1HIF1AVDRUSP2CASP7 | |
| SCHEMBL6428952 | 0.89 | GPBAR1 (0.70) | GPBAR1HIF1AVDRUSP2CASP7 | |
| SCHEMBL8965370 | 0.82 | GPBAR1 (0.78) | GPBAR1HIF1AVDRCYP2C9USP2 | |
| SCHEMBL16225763 | 0.82 | NPC1L1 (0.64) | USP2LMNATP53MEN1KMT2A | |
| SCHEMBL16226626 | 0.82 | NPC1L1 (0.64) | USP2LMNATP53MEN1KMT2A | |
| SCHEMBL16226433 | 0.82 | NPC1L1 (0.64) | USP2LMNATP53MEN1KMT2A | |
| SCHEMBL10932516 | 0.77 | GPBAR1 (0.54) | GPBAR1HIF1AVDRUSP2CASP7 | |
| SCHEMBL935606 | 0.77 | GPBAR1 (0.54) | GPBAR1HIF1AVDRUSP2CASP7 | |
| SCHEMBL15156946 | 0.77 | GPBAR1 (0.54) | GPBAR1HIF1AVDRUSP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255566-A2 | PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS | Yoo, Seo Hong (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001056547-A2 | PREPARATION OF AQUEOUS CLEAR SOLUTION DOSAGE FORMS WITH BILE ACIDS | YOO SEO HONG (US) | 2001-08-09 | — | — | WO | disclosed |