Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 8/20 | 0.43 |
| ▸ | ACHE | P22303 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7607919 | 1.00 | SLC2A1 (0.53) | SLC2A1MAPTTRPV1TP53HTT | |
| SCHEMBL7614269 | 0.93 | SLC2A1 (0.52) | SLC2A1MAPTTP53HTTBCHE | |
| SCHEMBL7614271 | 0.93 | SLC2A1 (0.52) | SLC2A1MAPTTP53HTTBCHE | |
| SCHEMBL7612324 | 0.90 | SLC2A1 (0.53) | SLC2A1MAPTTRPV1TP53BCHE | |
| SCHEMBL7612332 | 0.90 | SLC2A1 (0.53) | SLC2A1MAPTTRPV1TP53BCHE | |
| SCHEMBL7609148 | 0.89 | SLC2A1 (0.53) | SLC2A1MAPTTRPV1TP53HTT | |
| SCHEMBL7609152 | 0.89 | SLC2A1 (0.53) | SLC2A1MAPTTRPV1TP53HTT | |
| SCHEMBL7615413 | 0.88 | SLC2A1 (0.47) | SLC2A1MAPTTP53BCHEACHE | |
| SCHEMBL7615418 | 0.88 | SLC2A1 (0.47) | SLC2A1MAPTTP53BCHEACHE | |
| SCHEMBL7614313 | 0.88 | SLC2A1 (0.56) | SLC2A1MAPTTRPV1TP53BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |