Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 14/20 | 0.54 |
| ▸ | ACHE | P22303 | 13/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613705 | 0.95 | BCHE (0.54) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7607949 | 0.88 | SLC2A1 (0.66) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7607946 | 0.88 | SLC2A1 (0.66) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7613677 | 0.87 | BCHE (0.65) | BCHEACHESLC2A1TRPV1MEN1 | |
| SCHEMBL7613701 | 0.85 | SLC2A1 (0.60) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7613697 | 0.85 | SLC2A1 (0.60) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7622423 | 0.85 | BCHE (0.55) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7605752 | 0.85 | BCHE (0.58) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7606658 | 0.85 | BCHE (0.55) | BCHEACHESLC2A1TRPV1POLB | |
| SCHEMBL7681881 | 0.85 | BCHE (0.58) | BCHEACHESLC2A1TRPV1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |