Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PRPS1 | P60891 | 3/20 | 0.35 |
| ▸ | KMT5B | Q4FZB7 | 1/20 | 0.32 |
| ▸ | KMT5C | Q86Y97 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608610 | 1.00 | CCNT1 (0.41) | CCNT1CDK9HDAC6PRPS1KMT5B | |
| SCHEMBL7608607 | 0.90 | CCNT1 (0.46) | CCNT1CDK9HDAC6PRPS1KMT5B | |
| SCHEMBL7608598 | 0.90 | CCNT1 (0.46) | CCNT1CDK9HDAC6PRPS1KMT5B | |
| SCHEMBL7608602 | 0.90 | CCNT1 (0.46) | CCNT1CDK9HDAC6PRPS1KMT5B | |
| SCHEMBL8794070 | 0.81 | CCNT1 (0.40) | CCNT1CDK9HDAC6IRAK4MAPK14 | |
| SCHEMBL8794075 | 0.81 | CCNT1 (0.40) | CCNT1CDK9HDAC6IRAK4MAPK14 | |
| SCHEMBL9062639 | 0.80 | HDAC6 (0.43) | CCNT1CDK9HDAC6IRAK4AHCY | |
| SCHEMBL9062645 | 0.80 | HDAC6 (0.43) | CCNT1CDK9HDAC6IRAK4AHCY | |
| SCHEMBL7611059 | 0.80 | CCNT1 (0.45) | CCNT1CDK9HDAC6PRPS1AHCY | |
| SCHEMBL7643447 | 0.80 | CCNT1 (0.45) | CCNT1CDK9HDAC6PRPS1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455507-B1 | E.G., 2-BROMO-5,6-DICHLORO-1-BETA-D-RIBOPYRANOSYL-1H-BENZIMIDAZOLE; VIRICIDES, ESPECIALLY INFECTIONS OF HERPES AND CYTOMEGALO VIRUSES | SMITHKLINE BEECHAM CORPORATION | 2002-09-24 | — | — | US | disclosed |
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | GLAXO WELLCOME INC. | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020094963-A1 | BENZIMIDAZOLE DERIVATIVES | ZC3HAV1, BRPF3, BRD3 | CCNT1 483/4885CDK9 138/4885HDAC6 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.