SCHEMBL7609039

SCHEMBL7609039

C1=CC2=c3ccccc3=C(CCC3c4ccccc4-c4ccccc43)C2C=C1.[Hf]

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.33
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558691 0.97 HTR2A (0.33) HTR2ATDO2
SCHEMBL7603806 0.97 HTR2A (0.33) HTR2ATDO2
Hydrochloric Acid SCHEMBL5357882 0.96 HTR2A (0.33) HTR2A
Hydrochloric Acid SCHEMBL9245131 0.96 HTR2A (0.33) HTR2A
Hydrochloric Acid SCHEMBL5348066 0.96 HTR2A (0.33) HTR2A
Hydrochloric Acid SCHEMBL5357557 0.96 HTR2A (0.33) HTR2A
SCHEMBL7604909 0.93 HTR2A (0.33) HTR2A
SCHEMBL7605851 0.91 HTR2A (0.33) HTR2A
Hydrochloric Acid SCHEMBL5352655 0.90 HTR2A (0.32) HTR2A
Hydrochloric Acid SCHEMBL5353734 0.90 HTR2A (0.32) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0524624-B1 Use of organometallic flurorenyl compounds. PHILLIPS PETROLEUM CO (US) 2002-05-15 EP claimed
US-6162936-A Organometallic fluorenyl compounds, preparation, and use PHILLIPS PETROLEUM COMPANY (US) 2000-12-19 US disclosed
US-5571880-A CATALYSTS FOR POLYMERIZATION OF OLEFINS ESPECIALLY TO OBTAIN SYNDIOTACTIC POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1996-11-05 US disclosed
US-5436305-A Preparing polymer catalysts by reaction of alkali metal alkyl and fluorenyl in solvent PHILLIPS PETROLEUM COMPANY (US) 1995-07-25 US disclosed