Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609061 | 1.00 | BCHE (0.62) | BCHESLC2A1MCHR1KMT2AHTR2C | |
| SCHEMBL7606980 | 0.94 | SLC2A1 (0.64) | BCHESLC2A1MCHR1HTR2CSMN1; SMN2 | |
| SCHEMBL7606974 | 0.94 | SLC2A1 (0.64) | BCHESLC2A1MCHR1HTR2CSMN1; SMN2 | |
| SCHEMBL7606779 | 0.94 | SLC2A1 (0.64) | BCHESLC2A1MCHR1HTR2CABCG2 | |
| SCHEMBL7606785 | 0.94 | SLC2A1 (0.64) | BCHESLC2A1MCHR1HTR2CABCG2 | |
| SCHEMBL7609068 | 0.88 | BCHE (0.62) | BCHESLC2A1KMT2ARAB9AHPGD | |
| SCHEMBL7608566 | 0.86 | SLC2A1 (0.65) | BCHESLC2A1MCHR1KMT2AHTR2C | |
| SCHEMBL7608569 | 0.86 | SLC2A1 (0.65) | BCHESLC2A1MCHR1KMT2AHTR2C | |
| SCHEMBL7605978 | 0.85 | BCHE (0.58) | BCHESLC2A1KMT2ARAB9AHPGD | |
| SCHEMBL7605980 | 0.85 | BCHE (0.58) | BCHESLC2A1KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |