SCHEMBL7609150

SCHEMBL7609150

CSc1sc(C(=N)N)cc1-c1csc(Nc2ccc(Cl)cc2C=O)n1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLAU P00749 19/20 0.77
C1S P09871 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6921118 0.87 PLAU (1.00) PLAUC1S
Hydrochloric Acid SCHEMBL6920517 0.86 PLAU (0.98) PLAUC1S
SCHEMBL6927765 0.86 PLAU (0.81) PLAUC1S
SCHEMBL6926957 0.81 PLAU (1.00) PLAU
Hydrochloric Acid SCHEMBL6924685 0.81 PLAU (0.98) PLAU
SCHEMBL6924572 0.80 PLAU (0.85) PLAU
SCHEMBL6921325 0.79 PLAU (1.00) PLAU
SCHEMBL6927014 0.79 PLAU (1.00) PLAU
Hydrochloric Acid SCHEMBL6920895 0.79 PLAU (0.84) PLAU
SCHEMBL6921738 0.79 PLAU (1.00) PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020037915-A1 Compounds and compositons for treating C1s-mediated diseases and conditions 3-DIMENSIONAL PHARMACEUTICALS, INC. 2002-03-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020037915-A1 Compounds and compositons for treating C1s-mediated diseases and conditions C1S, C1R, C9 PLAU 229/4885C1S 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.