Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.58 |
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.53 |
| ▸ | DHODH | Q02127 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 3/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ACACA | Q13085 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25416501 | 0.89 | KDM4E (0.61) | TOP1KDM4ERXFP1DHODHLMNA | |
| SCHEMBL31222459 | 0.88 | KDM4E (0.57) | TOP1KDM4ERXFP1DHODHTSHR | |
| Bromide SCHEMBL31222446 | 0.88 | KDM4E (0.59) | TOP1KDM4ERXFP1DHODHLMNA | |
| SCHEMBL19050514 | 0.85 | KDM4E (0.54) | KDM4ERXFP1DHODHLMNATSHR | |
| SCHEMBL31222448 | 0.85 | TOP1 (0.61) | TOP1KDM4ERXFP1DHODHTSHR | |
| SCHEMBL8657096 | 0.84 | TOP1 (0.63) | TOP1SQORKDM4EGRM2DHODH | |
| SCHEMBL29397116 | 0.83 | TOP1 (0.66) | TOP1SQORKDM4EGRM2DHODH | |
| SCHEMBL670148 | 0.83 | GRM2 (0.60) | TOP1SQORKDM4EGRM2DHODH | |
| SCHEMBL31592763 | 0.83 | GRM2 (0.60) | TOP1SQORKDM4EGRM2DHODH | |
| SCHEMBL28251705 | 0.83 | TOP1 (0.66) | TOP1SQORKDM4EGRM2DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020151659-A1 | Formed from 6,6'-bis(2-(4-fluorophenyl)-4- phenylquinoline) and 4,4'-(1,1,1,3,3,3-hexafluoro-2,2-propylidene)bisphenol and 2,2-bis((4-maleimidophenoxy)phenyl)propane; dielectrics | HITACHI CHEMICAL CO., LTD. (JP) | 2002-10-17 | — | — | US | disclosed |