SCHEMBL7609456

SCHEMBL7609456

CCCCCO[C@@H]1O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.59
THRB P10828 1/20 0.59
HSD17B10 Q99714 1/20 0.59
CA2 P00918 10/20 0.54
NR3C1 P04150 1/20 0.51
FYN P06241 1/20 0.51
ADRA2A P08913 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ADRA2B P18089 1/20 0.51
DRD4 P21917 1/20 0.51
DRD3 P35462 1/20 0.51
TSHR P16473 1/20 0.48
CA12 O43570 9/20 0.47
CA1 P00915 9/20 0.47
CA9 Q16790 7/20 0.47
PKM P14618 1/20 0.46
MAPT P10636 1/20 0.45
MAPK1 P28482 1/20 0.45
CA4 P22748 2/20 0.45
CA5A P35218 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13528393 1.00 CYP2D6 (0.59) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL31252904 0.99 CYP2D6 (0.57) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL5181975 0.99 CYP2D6 (0.57) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL28815032 0.99 CYP2D6 (0.57) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL10495764 0.97 CYP2D6 (0.55) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL10360215 0.96 CYP2D6 (0.60) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL22083616 0.96 CYP2D6 (0.60) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL9617877 0.95 CYP2D6 (0.53) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL20711440 0.95 CYP2D6 (0.58) CYP2D6THRBHSD17B10CA2NR3C1
SCHEMBL2927855 0.94 CYP2D6 (0.53) CYP2D6THRBHSD17B10CA2NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6417380-B1 POLYCYCLOALKYL KETONE CONTAINING FLUORESCENT CHROMOPHORE IS ALKYLATED TO POLYCYCLOALKYLIDENE ETHER IN PRESENCE OF ALKALI METAL ALKOXIDE IN POLAR APROTIC SOLVENT APPLIED BIOSYSTEMS, LLC 2002-07-09 US disclosed
US-6124478-A Methods of using 1,2-dioxetanes and kits therefore TROPIX, INC. (US) 2000-09-26 US disclosed
US-5856522-A Method of using synthesis of 1,2-dioxetanes and kits therefore TROPIX, INC. (US) 1999-01-05 US disclosed
US-5777133-A Synthesis of 1, 2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1998-07-07 US disclosed
US-5679802-A 1,2-dioxetanes useful in chemiluminescent immunoassays TROPIX, INC. (US) 1997-10-21 US disclosed
US-5648555-A Alkenes APPLIED BIOSYSTEMS, LLC 1997-07-15 US disclosed
US-5639907-A Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1997-06-17 US disclosed
US-5637747-A Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1997-06-10 US disclosed
US-5625077-A 1,2-dioxetanes TROPIX, INC. (US) 1997-04-29 US disclosed
EP-0582317-A2 Synthesis of 1,2-dioxetanes and intermediates therefor TROPIX, INC. (US) 1994-02-09 EP disclosed
US-5177241-A SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR APPLIED BIOSYSTEMS, LLC 1993-01-05 US disclosed
US-4956477-A Synthesis of 1,2-dioxetanes TROPIX, INC. (US) 1990-09-11 US disclosed
EP-0368946-A1 1,2-DIOXETANES. QUEST SYSTEMS INC (US) 1990-05-23 EP disclosed
EP-0368946-A4 1,2-DIOXETANES. QUEST SYSTEMS INC (US) 1990-05-14 EP disclosed
WO-1989006226-A1 SYNTHESIS OF 1,2-DIOXETANES AND INTERMEDIATES THEREFOR QUEST SYSTEMS, INC. (US) 1989-07-13 WO disclosed