SCHEMBL7609541

SCHEMBL7609541

C=CCOc1nsnc1C1=CCCN(C)C1

nearest known ligand 0.77

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CHRM4 P08173 5/20 0.74
CHRM1 P11229 17/20 0.73
CHRM2 P08172 2/20 0.71
CHRM5 P08912 2/20 0.71
CHRM3 P20309 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL8629348 0.93 CHRM1 (0.71) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6906570 0.89 CHRM4 (0.81) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL7612265 0.88 CHRM1 (0.80) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6911734 0.87 CHRM1 (0.82) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6915589 0.85 CHRM1 (0.73) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6915593 0.85 CHRM1 (0.73) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6917329 0.85 CHRM4 (0.71) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6915584 0.85 CHRM1 (0.73) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6912678 0.84 CHRM1 (0.72) CHRM4CHRM1CHRM2CHRM5CHRM3
SCHEMBL6912682 0.84 CHRM1 (0.72) CHRM4CHRM1CHRM2CHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0734259-B1 Use of piperidine compounds in the treatment of schizophrenia NOVO NORDISK AS (DK) 2002-06-12 EP claimed
EP-0866702-A1 METHOD FOR TREATING PAIN ELI LILLY AND COMPANY (US) 1998-09-30 EP claimed
US-5753683-A SCHIZOPHRENIA NOVO NORDISK A/S (DK) 1998-05-19 US claimed
US-5744489-A ADMINISTERING CERTAIN 1,2,5-THIADIAZOLE AND 1,2,5-OXADIAZOLE COMPOUNDS GREENWOOD BEVERLEY (US) 1998-04-28 US claimed
US-5712297-A COGNITION ACTIVATORS; ALZHEIMER*S DISEASE NOVO NORDISK A/S (DK) 1998-01-27 US claimed
WO-1997020556-A9 METHOD FOR TREATING PAIN 1997-10-02 WO claimed
EP-0788357-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1997-08-13 EP claimed
WO-1997020556-A1 METHOD FOR TREATING PAIN ELI LILLY AND COMPANY (US) 1997-06-12 WO claimed
EP-0734259-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1996-10-02 EP claimed
WO-1996014066-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO claimed
WO-1996013168-A1 METHOD FOR TREATING ANXIETY ELI LILLY AND COMPANY (US) 1996-05-09 WO claimed
EP-0709095-A2 Method for treating anxiety using a tetrahydropyridine or azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP claimed
EP-0384288-B1 Piperidine compounds and their preparation and use NOVO NORDISK AS (DK) 1995-05-24 EP claimed
WO-1995005174-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO claimed
EP-0384288-A2 Piperidine compounds and their preparation and use NOVO NORDISK A/S (DK) 1990-08-29 EP claimed
EP-0709094-B1 Tetrahydropyridine oxadiazole or thiadiazole compound for treating anxiety LILLY CO ELI (US) 2000-04-05 EP disclosed
EP-0709095-B1 Method for treating anxiety using a tetrahydropyridine or azabicyclic oxadiazole or thiadiazole compound LILLY CO ELI (US) 1999-01-20 EP disclosed
EP-0709094-A2 Method for treating anxiety using a tetrahydropyridine oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
EP-0709095-A2 Method for treating anxiety using a tetrahydropyridine or azabicyclic oxadiazole or thiadiazole compound ELI LILLY AND COMPANY (US) 1996-05-01 EP disclosed
US-5488056-A 1,2,5-THIADIAZOLE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-01-30 US disclosed