Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7609651 | 1.00 | SLC2A1 (0.59) | SLC2A1MCHR1HTR2CCA12CA1 | |
| SCHEMBL7612377 | 0.94 | SLC2A1 (0.60) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7612381 | 0.94 | SLC2A1 (0.60) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7609652 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7609657 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CBCHEACHE | |
| SCHEMBL7606797 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CCA12CA1 | |
| SCHEMBL7620216 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CCA12CA1 | |
| SCHEMBL7620213 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CCA12CA1 | |
| SCHEMBL7606792 | 0.91 | SLC2A1 (0.58) | SLC2A1MCHR1HTR2CCA12CA1 | |
| SCHEMBL7655078 | 0.88 | SLC2A1 (0.73) | SLC2A1MCHR1HTR2CBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | claimed |
| JP-2002521441-A | — | — | 2002-07-16 | — | — | JP | claimed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | claimed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | claimed |
| EP-1100495-A4 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORP (US) | 2002-09-25 | — | — | EP | disclosed |
| EP-1100495-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000006153-A1 | PROPENAMIDES AS CCR5 MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-10 | — | — | WO | disclosed |