SCHEMBL7609768

SCHEMBL7609768

CCCN(c1ccncc1)n1ccc2cc(OC)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL7610936 0.91 SLC6A2 (0.82) SLC6A2
Maleic Acid SCHEMBL7610929 0.91 SLC6A2 (0.82) SLC6A2
SCHEMBL8637908 0.89 SLC6A2 (0.80) SLC6A2
SCHEMBL8539041 0.83 SLC6A2 (0.71) SLC6A2
SCHEMBL8539715 0.83 SLC6A2 (0.71) SLC6A2
SCHEMBL8538709 0.82 SLC6A2 (0.70) SLC6A2
SCHEMBL8441967 0.82 SLC6A2 (0.73) SLC6A2
SCHEMBL7612021 0.82 SLC6A2 (1.00) SLC6A2
SCHEMBL7608039 0.82 SLC6A2 (1.00) SLC6A2
SCHEMBL9738329 0.82 SLC6A2 (0.69) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP claimed
EP-0840609-A1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1998-05-13 EP claimed
WO-1997004777-A1 USE OFF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS HOECHST MARION ROUSSEL, INC. (US) 1997-02-13 WO claimed
US-4880822-A COGNITION ACTIVATORS, ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-11-14 US claimed
EP-0840609-B1 USE OF UNSUBSTITUTED AND SUBSTITUTED N-(PYRROL-1-YL)PYRIDINAMINES AS ANTICONVULSANT AGENTS AVENTIS PHARMA INC (US) 2002-06-05 EP disclosed
EP-0635269-B1 Use of N-(Pyridinyl)-1H-Indol-1-Amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders HOECHST MARION ROUSSEL INC (US) 1999-11-03 EP disclosed
US-5776955-A Use of unsubstituted and substituted n-(pyrrol-1-yl)pyridinamines as anticonvulsant agents HOECHST MARION ROUSSEL, INC. 1998-07-07 US disclosed
EP-0635269-A1 Use of N-(Pyridinyl)-1H-Indol-1-Amines for the preparation of a medicament for the treatment of obsessive-compulsive disorders HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1995-01-25 EP disclosed
EP-0287982-B1 N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1994-12-07 EP disclosed
US-5356910-A Use of N-(pyridinyl)-1H-indol-1-amines for the treatment of obsessive-compulsive disorder HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1994-10-18 US disclosed
US-5039811-A Analgesics, antidepressants, memory activators; condensation, reduction HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-08-13 US disclosed
US-4970218-A ANALGESIC, ANTIDEPRESSANT, MEMORY ENHANCEMENT HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-11-13 US disclosed
US-4880822-A COGNITION ACTIVATORS, ANALGESICS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1989-11-14 US disclosed
EP-0287982-A2 N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1988-10-26 EP disclosed