Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4883151 | 1.00 | BACE1 (0.88) | BACE1BACE2 | |
| SCHEMBL4890158 | 0.95 | BACE1 (0.85) | BACE1BACE2 | |
| SCHEMBL7609512 | 0.94 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL4890168 | 0.94 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL4882945 | 0.94 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL4882942 | 0.94 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL4892707 | 0.93 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL4892714 | 0.93 | BACE1 (1.00) | BACE1BACE2 | |
| SCHEMBL7607163 | 0.93 | BACE1 (0.84) | BACE1BACE2 | |
| SCHEMBL4890341 | 0.93 | BACE1 (0.84) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265849-A2 | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001070672-A2 | COMPOUNDS AND METHODS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2001-09-27 | — | — | WO | disclosed |