Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 13/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 13/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7610399 | 0.90 | MEN1 (0.71) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL7615176 | 0.88 | MAPT (0.72) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL20049939 | 0.83 | MEN1 (0.75) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| Hydrochloric Acid SCHEMBL7081769 | 0.82 | MAPT (0.55) | ADRB1ADRB3MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7081767 | 0.82 | MAPT (0.55) | ADRB1ADRB3MAPTMEN1KMT2A | |
| SCHEMBL7606856 | 0.80 | MEN1 (0.63) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL11606524 | 0.78 | MEN1 (0.71) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL7612538 | 0.78 | MEN1 (0.71) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL6327240 | 0.77 | MEN1 (0.70) | ADRB1ADRB3MAPTMEN1OPRM1 | |
| SCHEMBL7033981 | 0.77 | MEN1 (0.70) | ADRB1ADRB3MAPTMEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1230210-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001036375-A1 | AMINOALCOHOL DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-25 | — | — | WO | disclosed |