⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654087 | 0.75 | TSHR (0.41) | — | |
| SCHEMBL6200806 | 0.73 | — | — | |
| SCHEMBL9939600 | 0.73 | — | — | |
| SCHEMBL9428529 | 0.73 | — | — | |
| SCHEMBL17378568 | 0.71 | — | — | |
| SCHEMBL8698477 | 0.71 | — | — | |
| SCHEMBL953966 | 0.71 | — | — | |
| SCHEMBL8340714 | 0.70 | — | — | |
| SCHEMBL2129023 | 0.70 | — | — | |
| SCHEMBL23892733 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024041586-A1 | PRODRUG OF JAK KINASE INHIBITOR | 启元生物(杭州)有限公司 | 2024-02-29 | — | — | WO | disclosed |
| EP-1194414-A1 | PROCESS FOR PREPARING 2-AMINO-4-(4-FLUORPHENYL)-6-ALKYLPYRIMIDINE-5-CARBOXYLATE | Lonza AG (CH) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001004100-A1 | PROCESS FOR PREPARING 2-AMINO-4-(4-FLUORPHENYL)-6-ALKYLPYRIMIDINE-5-CARBOXYLATE | LONZA AG (CH) | 2001-01-18 | — | — | WO | disclosed |
| EP-0975594-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | Pfizer Limited (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1999002493-A1 | PROCESS FOR THE PRODUCTION OF INDOLE DERIVATIVES | PFIZER LIMITED (GB) | 1999-01-21 | — | — | WO | disclosed |