Oxalic Acid

Oxalic Acid

SCHEMBL7613445

CN1CCC=C(c2nsnc2SCCCc2cccs2)C1.O=C(O)C(=O)O

nearest known ligand 0.89

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1SLC6A4

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 10/20 0.64
CHRM4 P08173 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7613768 0.94 CHRM1 (0.72) CHRM1CHRM4
Oxalic Acid SCHEMBL7617867 0.89 CHRM1 (0.59) CHRM1CHRM4
Oxalic Acid SCHEMBL7616276 0.87 CHRM1 (0.69) CHRM1CHRM4
Oxalic Acid SCHEMBL7617850 0.84 CHRM1 (0.74) CHRM1CHRM4
Oxalic Acid SCHEMBL7621728 0.84 CHRM1 (0.69) CHRM1CHRM4
Oxalic Acid SCHEMBL7611050 0.83 CHRM1 (0.77) CHRM1CHRM4
Oxalic Acid SCHEMBL7614723 0.83 CHRM1 (0.79) CHRM1CHRM4
Oxalic Acid SCHEMBL7610942 0.83 CHRM1 (0.77) CHRM1CHRM4
Oxalic Acid SCHEMBL7612009 0.83 CHRM1 (0.64) CHRM1CHRM4
SCHEMBL7609700 0.82 CHRM1 (0.67) CHRM1CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0734259-B1 Use of piperidine compounds in the treatment of schizophrenia NOVO NORDISK AS (DK) 2002-06-12 EP disclosed
US-RE36375-E Treatment of Alzheimer's disease using azacyclic compounds NOVO NORDISK A/S (DK) 1999-11-02 US disclosed
US-5919805-A 3-OXY- OR THIO-DERIVATIVES OF 1,2,5-OXADIAZOLES OR 1,2,5-THIADIAZOLES; TREATMENT OF ALZHEIMER'S DISEASE, SEVERE PAINFUL CONDITIONS AND GLAUCOMA. NOVO NORDISK A/S (DK) 1999-07-06 US disclosed
US-5773452-A ALZHEIMER'S DISEASE; COGNITION ACTIVATORS NOVO NORDISK ALS (DK) 1998-06-30 US disclosed
US-RE35822-E COGNITION ACTIVATORS NOVO NORDISK A/S (DK) 1998-06-09 US disclosed
US-5753683-A SCHIZOPHRENIA NOVO NORDISK A/S (DK) 1998-05-19 US disclosed
US-5750541-A 3-(1,2,5-THIA OR OXADIAZOL-3-YL)-1,2,5,6-PYRIDINE DERIVATIVES; SCHIZOPHRENIFORM DISEASES; SIDE EFFECT REDUCTION NOVO NORDISK A/S (DK) 1998-05-12 US disclosed
US-5744489-A ADMINISTERING CERTAIN 1,2,5-THIADIAZOLE AND 1,2,5-OXADIAZOLE COMPOUNDS GREENWOOD BEVERLEY (US) 1998-04-28 US disclosed
US-5658932-A AZACYCLIC COMPOUNDS; COGNITIVE FUNCTION STIMULANTS; ALZHEIMER'S DISEASE NOVO NORDISK A/S (DK) 1997-08-19 US disclosed
EP-0788357-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1997-08-13 EP disclosed
EP-0734259-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1996-10-02 EP disclosed
EP-0732925-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1996-09-25 EP disclosed
US-5559136-A Treatment of Alzheimer's disease using azacyclic compounds NOVO NORDISK A/S (DK) 1996-09-24 US disclosed
US-5545638-A USING A 3-(TETRAHYDROPYRID-3-YL-) SUBSTITUTED (OXA- OR THIA-)DIAZOLE COMPOUND NOVO NORDISK A/S (DK) 1996-08-13 US disclosed
WO-1996014066-A1 A METHOD OF TREATING URINARY BLADDER DYSFUNCTIONS NOVO NORDISK A/S (DK) 1996-05-17 WO disclosed
EP-0687265-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1995-12-20 EP disclosed
WO-1995017185-A1 A METHOD OF TREATING GASTROINTESTINAL MOTILITY DISORDERS NOVO NORDISK A/S (DK) 1995-06-29 WO disclosed
WO-1995005174-A1 ANTIPSYCHOTIC METHOD NOVO NORDISK A/S (DK) 1995-02-23 WO disclosed
US-5376668-A Cholinergic agents as cognition activators in treatment of Alzheimer*s disease NOVO NORDISK A/S (DK) 1994-12-27 US disclosed
WO-1994020495-A1 HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE NOVO NORDISK A/S (DK) 1994-09-15 WO disclosed